Targeting unmet needs in the treatment of cancer through innovative drug development strategies have witnessed favorable outcomes recently. New targets have been validated in this process where kinases lead the way. Approval of Kyprolis (carfilzomib, Onyx), Pomalyst (pomalidomide, Celgene) for the Relapsed and Refractory Multiple Myeloma (RRMM) and their successful commercial launch validate the strategy deployed by the companies. We expect a similar scenario to unfold in the treatment of recurrent/ refractory MDS (RR-MDS, High-Risk MDS), and AML (relapsed/ refractory AML, R/R AML). Innovative approach to treating unmet need has been handsomely rewarded in the past through in-licensing or outright …
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